5-Methoxy-UTP

5moUTP

5-Methoxyuridine-5'-triphosphate, Sodium Salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-972S 10 μl (100 mM)Sob demanda Adicionar ao Carrinho
NU-972L 5 x 10 μl (100 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 5-Methoxy-UTP (5moUTP, 5-Methoxyuridine-5'-triphosphate, Sodium Salt)
Structural formula of 5-Methoxy-UTP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H17N2O16P3 (free acid)

Peso molecular: 514.17 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 100 mM - 110 mM

pH: 7.5 ±0.5

Solubilidade: water

Propriedades espectroscópicas: λmax 278 nm, ε 8.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Produtos relacionados: HighYield T7 RNA Synthesis Kit, #RNT-101

Referências selecionadas:
An et al. (2019) Long-term efficacy and safety of mRNA therapy in two murine models of methylmalonic acidemia. EBioMedicine 45:519.

Novakowski et al. (2019) Delivery of mRNA to platelets using lipid nanoparticles. Sci. Rep. 9 (1):552.

An et al. (2017) Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia. Cell Rep. 21 (12):3548.

Li et al. (2016) Effects of Chemically Modified Messenger RNA on Protein Expression Bioconjugate Chem. 27:849.