Other Marker Nucleosides
8-Oxo-2’-deoxyguanosine serves as a biomarker of oxidative stress.[1-3]
Selected References
[1] Lee et al. (2010) Urine 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a specific marker of oxidative stress, using direct, isocratic LC-MS/MS: Method evaluation and application in study of biological variation in healthy adults. Clin. Chim. Acta 411 (5-6):416.
[2] Sharma et al. (2004) Biological relevance of adduct detection to the chemoprevention of cancer. Clin. Cancer Res. 10 (15):4901.
[3] Churchwell et al. (2002) Quantification of multiple DNA adducts formed through oxidative stress using liquid chromatography and electrospray tandem mass spectrometry. Chem. Res. Toxicol. 15:1295.