TNP-GDP

2',3'-O-Trinitrophenyl-guanosine-5'-diphosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-217S 1 μmolSob demanda Adicionar ao Carrinho
NU-217L 5 x 1 μmolSob demanda Adicionar ao Carrinho
Structural formula of TNP-GDP (2',3'-O-Trinitrophenyl-guanosine-5'-diphosphate, Triethylammonium salt)
Structural formula of TNP-GDP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C16H16N8O17P2

Peso molecular: 654.29 g/mol

Pureza: ≥ 95 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 252/408/470 nm, ε 24.1/26.5/18.3 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm

Referências selecionadas:
Suryanarayana et al. (2009) Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2',3'-O- (2,4,6-Trinitrophenyl)- Substituted Nucleoside 5'-Triphosphates. J. Pharmacol. Exp. Ther. 330 (3):687.

Sprang et al. (2006) Broad Specifity of Mammalian Adenylyl Cyclase for Interaction with 2',3'-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Mol. Pharmacol. 70:878.

Hiratsuka (1985) A chromophoric and fluorescent analog of GTP, 2',3'-O- (2,4,6-trinitrocyclohexadienylidene)-GTP, as a spectroscopic probe for the GTP inhibitory site of liver glutamate dehydrogenase. J. Biol. Chem. 260 (8):4784.