Mant-dGTP
3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-triphosphate, Triethylammonium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-212S | 50 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-212L | 5 x 50 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C18H23N6O14P3 (free acid)
Peso molecular: 640.33 g/mol (free acid)
CAS#: 124615-99-2
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm
Formulários:
Resonance energy transfer studies (FRET)[1]
Enzyme kinetic studies[2]
Specific Ligands:
Bacillus anthraxis toxin edema factor[1]
EF-Tu[3]
Referências selecionadas:
[1] Suryanarayana et al. (2009) Distinct interactions of 2'- and 3'-O- (N-methyl)anthraniloyl-isomers of ATP and GTP with the adenylyl cyclase toxin of Bacillus anthracis, edema factor. Biochemical Pharmacology 78 (3):224.
[2] Kettlun et al. (2005) Potato tuber isoapyrases:Substrate specifity, affinity labelling, and proteolytic susceptibility. Phytochemistry 66:975.
[3] Rodnina et al. (1995) Codon-dependent conformational change of elongation-factor tu preceding GTP hydrolysis on the ribosome. EMBO J. 14 (11):2613.
Hazlett et al. (1993) Solution dynamics of p21 (Ras)proteins bound with fluorescent nucleotides - a time-resolved fluorescence study. Biochemistry-US 32 (49):13575.