Mant-dGDP

3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-205S 30 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-205L 5 x 30 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of Mant-dGDP (3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt)
Structural formula of Mant-dGDP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C18H22N6O11P2 (free acid)

Peso molecular: 560.35 g/mol (free acid)

CAS#: 127383-33-9

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 252/355 nm, ε 22.6/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm

Formulários:
Resonance energy transfer to Trp in protein cdc42hs[1]
Conformational analysis of Ras-like protein[2]

Specific Ligands:

Ras-like GTP-binding protein Cdc42Hs[1, 2]

Referências selecionadas:
[1] Leonard et al. (1994) Investigation of the GTP-binding GTPase cycle of cdc42hs using fluorescence spectroscopy. Biochemistry 33 (40):12323.

[2] Nomanbhoy et al. (1996) Investigation of the GTP-binding GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence. Biochemistry 35 (14):4602.

Liu et al. (2008) Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2. Molecular and cellular biology 28 (23):7109.