TNP-CTP

2',3'-O-Trinitrophenyl-cytidine-5'-triphosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-225S 100 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-225L 5 x 100 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of TNP-CTP (2',3'-O-Trinitrophenyl-cytidine-5'-triphosphate, Triethylammonium salt)
Structural formula of TNP-CTP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C15H17N6O20P3

Peso molecular: 694.24 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 272/408/470 nm, ε 9.1/26.4/18.5 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm

Referências selecionadas:
Suryanarayana et al. (2009) Differential Inhibition of Various Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by 2',3'-O- (2,4,6-Trinitrophenyl)- Substituted Nucleoside 5'-Triphosphates. J. Pharmacol. Exp. Ther. 330 (3):687.

Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.

Sprang et al. (2006) Broad Specifity of Mammalian Adenylyl Cyclase for Interaction with 2',3'-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Mol. Pharmacol. 70:878.