TNP-ADP

2',3'-O-Trinitrophenyl-adenosine-5'-diphosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-222S 1 μmolSob demanda Adicionar ao Carrinho
NU-222L 5 x 1 μmolSob demanda Adicionar ao Carrinho
Structural formula of TNP-ADP (2',3'-O-Trinitrophenyl-adenosine-5'-diphosphate, Triethylammonium salt)
Structural formula of TNP-ADP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C16H16N8O16P2

Peso molecular: 638.28 g/mol

CAS#: 77450-67-0

Pureza: ≥ 95 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 259/408/470 nm, ε 25.0/26.4/18.5 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 408/470 nm, λem 552 nm

Referências selecionadas:
Sprang et al. (2006) Broad Specifity of Mammalian Adenylyl Cyclase for Interaction with 2',3'-Substituted Purine- and Pyrimidine Nucleotide Inhibitors. Mol. Pharmacol. 70:878.

Qu et al. (2003) Stoichiometry and Affinity of Nucleotide Binding to P-Glycoprotein during the Catalytic Cycle. Biochemistry 42:1170.

Plesniak et al. (2002) Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry 41:13876.

Hirschman et al. (2001) Active site mutations in CheA, the signal-transducing protein kinase of the chemotaxis system in Escherichia coli. Biochemistry 40:13876.

Galletto et al. (2000) Interactions of nucleotide cofactors with the escherichia coli replication factor DnaC protein. Biochemistry 39:12959.

Weber et al. (1997) Binding of TNP-ATP and TNP-ADP to the non-catalytic sites of Escherichia coli F1-ATPase. FEBS Lett. 412:169.

Thomas et al. (1991) Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide. Science 251:555.

Kormer et al. (1982) Using 2' (3')-O-trinitrophenyl derivatives of adenine nucleotides to study the structure and mechanism of functioning of soluble mitochondrial ATPase. Eur. J. Biochem. 121:451.

Schafer et al. (1982) Interaction of high-affinity nucleotide binding sites in mitochondrial ATP synthesis and hydrolysis. Bioenerg. Biomembr. 14:479.

Tao et al. (1981) Excitation energy transfer studies on the proximity between SH1 and the adenosinetriphosphatase site in myosin subfragment 1. Biochemistry 20:5051.

Hiratsuka et al. (1977) Heterogeneous reaction of heavy meromyosin ATPase with 2' (or 3')-O- (2,4,6-trinitrophenyl)adenosine 5'-5'-triphosphate. J. Biochem. (Tokyo) 82:575.