anti-PML

anti-human PML

rabbit, polyclonal

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
ABD-030 50 μl Sob demanda Adicionar ao Carrinho

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
avoid freeze/thaw cycles, store in aliquots

Validade: 12 months

Forma: liquid (Supplied as serum)

Formulários:
Indirect Immunofluorescence 1:250. Western Blot 1:500

Descrição:
Polyclonal Antibody pABahPML(460-479)#3 to human PML.

Specificity:
Antibody specificity was evalutated by indirect immunoflourescence and western blotting (see Figure 1A and B). The antibody detects all PML isoforms according to Condemine et al. (2006).

Immunogen:
The antibody binds to a peptide corresponding to amino acids 460-479 (KGPSYGEDVSNTTTQKRKC) of the human PML protein. No cross reaction with mouse PML protein was observed in Western blots. The immunogen peptide sequence is not conserved in rat, chimpanzee, dog, or bovine PML proteins.

Referências selecionadas:
Krejcí et al. (2008) Nuclear organization of PML bodies in leukaemic and multiple myeloma cells. Leukemia Research 32:1866.

Condemine et al. (2006) Characterization of endogenous human promyelocytic leukemia isoforms. Cancer Res. 66:6192.