dUpNHp
(dUMPNP)
2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-902S | 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-902L | 5 x 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
![Structural formula of dUpNHp ((dUMPNP), 2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt)](/images/Structures/NU-902.png)
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C9H15N3O10P2 (free acid)
Peso molecular: 387.17 g/mol (free acid)
CAS#: 178809-71-7
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 262 nm, ε 10.2 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Kovári et al. (2008) Methylene substitution at the ab bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. J. Biol. Chem. 71:308.
Barabás et al. (2004) Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase. J. Biol. Chem. 279 (41):42907.
Persson et al. (1996) Synthesis of 2'-deoxyuridine 5'- (alpha,beta-imido)triphosphate: A substrate analogue and potent inhibitor of dUTPase. Bioorgan. Med. Chem. 4 (4):553.