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ApCpp

(AMPCPP)

Adenosine-5'-[(α,β)-methyleno]triphosphate, Sodium salt

α,β-Methyleneadenosine-5'-triphosphate

Datasheet (PDF)
Catálogo Nº Apresentação Preço (R$) Comprar
NU-421-2 2 mgSob demanda Adicionar ao Carrinho
NU-421-10 10 mgSob demanda Adicionar ao Carrinho
NU-421-25 25 mgSob demanda Adicionar ao Carrinho
Structural formula of ApCpp ((AMPCPP), Adenosine-5'-[(α,β)-methyleno]triphosphate, Sodium salt)
Structural formula of ApCpp

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C11H18N5O12P3 (free acid)

Peso molecular: 505.21 g/mol (free acid)

CAS#: 7292-42-4 (acid), 1343364-54-4 (Trisodium salt)

Pureza: ≥ 98 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Specific Ligands:

Nonhydrolyzable ligand for P2 purinoreceptor[1]

Referências selecionadas:
[1] Burnstock et al. (1985) Is there a basis for distinguishing two types of P2-purinoceptor≥ Gen. Pharmacol. 16:433.

Zebisch et al. (2012) Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (NTPDase) 1. Journal of molecular biology 415 (2):288.

Riballo et al. (2009) XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation. Nucleic Acids Research 37 (2):482.

Bivalacqua et al. (2002) Comparative responses to alpha,beta-methylene-ATP in cat pulmonary, mesenteric, and hindquarter vascular beds. Appl. Physiol. 93 (4):1287.

Trezise (1994) The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by a,b-methylene adenosine 5'-triphosphate. Br. J. Pharmacol. 112:282.

Bo (1995) Characterization and autoradiographic localization of [3H]α,β-methylene adenosine 5'-triphosphate binding sites in human urinary bladder. Br. J. Urol. 76:297.