ADPβS

For general laboratory use.

Envio: shipped on dry ice

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 6 months after date of delivery

Fórmula molecular: C10H15N5O9P2S (free acid)

Peso molecular: 443.26 g/mol (free acid)

CAS#: 35094-45-2 (free acid), 73536-95-5 (lithium salt)

Pureza: ≥ 85 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Please note: For reasons of stability, please make sure that the pH value of a solution of this product never drops below 7.0. This can be achieved by dissolving the nucleotide in a buffer of your choice (50 - 100 mM, pH 7 - 10). Dissolve and adjust concentration photometrically.

Referências selecionadas:
Isfort et al. (2011) Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent.J. Biol. Chem. 286 (52):44776.

Chang et al. (2005) Nitric Oxide-dependent Allosteric Inhibitory Role of a Second Nucleotide Binding Site in Soluble Guanylyl Cyclase. J. Biol. Chem. 280 (12):11513.

Goody et al. (1971) Thiophosphate Analogs of Nucleoside Di- and Triphosphates. J. Amer. Chem. Soc. 93:6252.