ZTP

(AICAR triphosphate)

5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-triphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1166S 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-1166L 5 x 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of ZTP ((AICAR triphosphate), 5'-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl-5'-triphosphate, Sodium salt)
Structural formula of ZTP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C9H17N4O14P3 (free acid)

Peso molecular: 498.17 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 265 nm, ε 12.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Corton et al. (1995) 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating protein kinase in intact cells≥ Eur J Biochem. 229:558.

Henin et al. (1995) Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 9:54.

Henin et al. (1996) Stimulation of rat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta. 1290:197.

Sullivan et al. (1994) Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 353:33.