Adenosine-3',5'-bisphosphate

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H15N5O10P2 (free acid)

Peso molecular: 427.20 g/mol (free acid)

CAS#: 1053-73-2

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 259 nm, ε 15.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Jacobson et al. (2001) Ribose modified nucleosides and nucleotides as ligands for purine receptors. Nucleos. Nucleot. Nucl. 20 (4-7):333.

Jung et al. (2001) Platelet collagen receptor integrin alpha (2)beta (1) activation involves differential participation of ADP-receptor subtypes P2Y1 and P2Y12 but not intracellular calcium change. Eur. J. Biochem. 268 (12):3513.

Sheng et al. (2001) Bacterial expression, purification, and characterization of rat hydroxysteroid sulfotransferase STa. Protein Expres. Purif. 21 (1):235.

Leonidas et al. (2001) Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN) - High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. J. Biol. Chem. 276 (18):15009.

Kakuta et al. (1998) The sulfuryl transfer mechanism - Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysis. J. Biol. Chem. 273 (42):27325.

Dichtl et al. (1997) Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J. 16 (23):7184.

Mandon et al. (1994) Purification of the Golgi Adenosine 3'-phosphate 5'-phosphosulfate transporter, a homodimer within the membrane. P. Natl. Acad. Sci. USA 91 (22):10707.

Yang et al. (1994) Acyl carrier protein (ACP) import into chloroplasts - covalent modification by a stromal holoACP synthase is stimulated by exogenously added CoA and inhibited by Adenosine 3',5'-bisphosphate. Eur. J. Biochem. 224 (2):743.

Lee et al. (1992) Purification and identification of the heat-stable factor required for pregnenolone-binding protein-activity - evidence that the factor is Adenosine 3',5'-diphosphate. J. Biol. Chem. 267 (16):10982.

Chung et al. (1978) Conformation of Adenosine 2',5'-diphosphate and Adenosine 3',5'-diphosphate. J. Carb.-Nucleos.-Nucl. 5 (6):469.

Subbarao et al. (1978) Adenosine-3',5'-diphosphate and Coenzyme-A - effects on platelet-function. Biochem. Pharmacol. 27 (8):1193.

McDonald et al. (1978) Inhibition of catalytic activity of bovine pancreatic ribonuclease by Adenosine-3',5' diphosphate. Fed. Proc. 37 (6):1806.