6-Mercaptopurine-riboside-5'-monophosphate
6-Thio-Inosine-5'-monophosphate
6-Mercaptopurine-riboside-5'-monophosphate, Sodium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-1148S | 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-1148L | 5 x 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C10H13N4O7PS (free acid)
Peso molecular: 364.26 g/mol (free acid)
CAS#: 53-83-8
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 322 nm, ε 27.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Neurath et al. (2005) 6-Thioguanosine Diphosphate and Triphosphate Levels in Red Blood Cells and Response to Azathioprine Therapy in Crohns Disease. Clinical Gastroenterology and Hepatology 3 (10): 1007.
Wielinga et al. (2002)Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Mol Pharmacol. 62 (6):1321.
Szabados et al. (1994) 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRFCEM leukemia cells: purification, pH dependence, and inhibitors. Biochemistry 33 (47):14237.
Stet et al. (1993) A biochemical basis for synergism of 6-mercaptopurine and mycophenolic acid in Molt F4, a human malignant T-lymphoblastic cell line. Biochim Biophys Acta. 1180 (3):277.
Drake et al. (1982) Metabolism and mechanisms of action of 9- (tetrahydro-2-furyl)-6-mercaptopurine in Chinese hamster ovary cells. Chem Biol Interact. 41 (1):105.