m7GMP
7-Methyl-guanosine-5'-monophosphate, Triethylammonium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-1135S | 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-1135L | 5 x 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C11H16N5O8P (free acid)
Peso molecular: 377.25 g/mol (free acid)
CAS#: 47442-17-1
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 258/280 nm, ε 9.8/8.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Formulários:
Association to human scavenger decapping enzyme[1]
Inhibition of methyltransferase activity[2]
Referências selecionadas:
[1] Darzynkiewicz et al. (2007) Interaction of human decapping scavenger with 5-mRNA cap analogues: structural requirements for catalytic activity. Journal of Physics: Condensed Matter 19:285217/1.
[2] Magden et al. (2001) Virus-specific mRNA capping enzyme encoded by hepatitis E virus. J. Virology 75:6249.
Shen et al. (2001) Structural and thermodynamic behavior of eukaryotic initiation factor 4E in supramolecular formation with 4E-binding protein 1 and mRNA cap analogue, studied by spectroscopic methods. Chem Pharm Bull 49 (10):1299.
Carberry et al. (1989) A spectroscopic study of the binding of m7GTP and m7GpppG to human protein synthesis initiation factor 4E. Biochemistry 28 (20):8078.
Beemon et al. (1977) In vitro translation yields a possible Rous sarcoma virus src gene product. Proc Natl Acad Sci U S A. 74 (8):3302.