Ac4GlcNAz

N-azidoacetylglucosamine-tetraacylated (Ac4GlcNAz)

Catálogo Nº Apresentação Preço (R$) Comprar
CLK-1085-5 5 mgSob demanda Adicionar ao Carrinho
CLK-1085-25 25 mgSob demanda Adicionar ao Carrinho
CLK-1085-100 100 mgSob demanda Adicionar ao Carrinho
Structural formula of Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated (Ac4GlcNAz))
Structural formula of Ac4GlcNAz

For general laboratory use.

Envio: shipped at ambient temperature

Condições de armazenamento: store at -20 °C

Validade: 12 months after date of delivery

Fórmula molecular: C16H22N4O10

Peso molecular: 430.37 g/mol

CAS#: 98924-81-3

Pureza: mass identification (ESI-MS)

Forma: amorphous solid

Solubilidade: DMSO, DMF, MeOH

Formulários:
Glycoconjugate synthesis monitoring by metabolic labeling

Descrição:
The tetraacetylated N-Azidoacetyl-glucosamine (Ac4GlcNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylglucosamine(GlcNAc).

The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.

Recommended concentration for metabolic labeling: 25-75 μM. This concentration range may serve as a starting point for an individual assay set-up.