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  2. Marcação DNA/RNA e Bio Moléculas
  3. Click Chemistry
  4. Reagentes Click por Química
  5. Reagentes TCO
  6. Reagentes Bifuncionais

Reagentes Bifuncionais contendo TCO

Table 1: Available Trans-Cyclooctene-containing Bifunctional Reagents

Functional GroupsTrans-Cyclooctene
NHS esterTCO-NHS ester
TCO-PEG4-NHS ester
MaleimideTCO-PEG3-Maleimide
Amine (-NH2)TCO-Amine

Selected References:

Selvaraj et al. (2013) trans-Cyclooctene - a stable voracious dienophile for bioorthogonal labeling. Current Opinion in Chemical Biology 17:753.